Cambodia — Angkor Wat, Phnom Penh and the southern coast — is most often visited as part of a wider Southeast Asia trip alongside Thailand and Vietnam. That’s worth flagging at your consult, because a multi-country itinerary can change what you need.

This guide covers the vaccinations and precautions Australians should consider for Cambodia in 2026. It is general information only and depends on your itinerary and health history.

Do you need vaccinations to travel to Cambodia?

No vaccinations are required for most Australians (a yellow fever certificate is only needed if arriving from a yellow fever country). The vaccines below are recommended for your own protection.

Recommended vaccinations for Cambodia

For almost every traveller

  • Hepatitis A — food- and water-borne; recommended for nearly all travellers.
  • Typhoid — recommended for most trips, particularly outside the main hotels.
  • Routine vaccines — tetanus, diphtheria, whooping cough, MMR (measles) and seasonal flu should be current.

Depending on your trip

  • Rabies — a genuine risk; worth discussing for rural travel, animal contact or children (see below).
  • Hepatitis B — for longer stays or possible medical, tattoo or personal exposures.
  • Japanese encephalitis — endemic in Cambodia; considered for longer or rural stays in agricultural areas.
  • Cholera — occasionally recommended for higher-risk itineraries.

Rabies and Japanese encephalitis

Rabies is present and almost always fatal once symptoms appear; a pre-exposure vaccine is worth discussing if you’ll be around animals, in rural areas, or travelling with children. Japanese encephalitis is endemic in rural rice-growing areas, so the vaccine is commonly considered for longer or rural stays.

Malaria and dengue

Malaria risk in Cambodia is mainly in rural and forested areas, including some border regions, and is generally low in Phnom Penh and the town of Siem Reap and around the main Angkor temples by day. Whether you need antimalarial tablets depends on your itinerary — this is an itinerary-by-itinerary decision.

Dengue is widespread and peaks in the wet season. Mosquito-bite prevention is essential: repellent with DEET or picaridin, long loose clothing, and screened or air-conditioned rooms. Ask a travel doctor whether the newer dengue vaccine (Qdenga, TGA-approved in April 2026, currently available in Australia only via the Special Access Scheme) suits you.

Food and water

Travellers’ diarrhoea is common. Drink sealed bottled or boiled water, be cautious with ice and raw foods, and choose busy outlets. A travel doctor can prescribe a treatment kit to carry.

When to see a travel doctor

Book your consultation 6 to 8 weeks before you fly, and mention any other countries on your trip so your plan covers the whole itinerary.

At Travel Doctors Brisbane in Bulimba, we tailor recommendations to your exact Cambodia (and multi-country) itinerary, prescribe what you need, and issue yellow fever certificates where required. See our Cambodia destination health advice, browse our travel health services, and book your consultation.

This article is general information only and current as at June 2026. It does not replace personalised medical advice. Always confirm current requirements with a qualified travel health professional and Smartraveller before you travel.

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Expert travel health advice from your friendly local doctors in Bulimba. Book your consultation today for a safe and healthy trip.